Parts of a muscle cell : Sarcolemma- muscle cell membrane, Sarcoplasmic Reticulum- ER in muscle, T tubule penetrate into cells and cotact SR
Calcium Release in muscle:
Motor neuron impulse arrives to axonal terminus, neuro muscular juction synapse passes message onto muscle cell, sarcolemma (muscle cell membrane) undergo action potential all along length of cell membrane and into T-tubule system, voltage change causes releases of Ca+2 ions into muscle cell. Calcium causes actin-myosin units sarcomers to shorten
Shortening of actin myosin units lead to whole muscle contraction, connection of many cells make whole muscle shorten bringing about body movements, movement happens across joints between skeletal elements
Joints:
connect skeletal elements, synovial joints are lubricated mobile joints, skeletal elements linked by synovial jounts move when muscle pull on those skeletal elements.
Flexion- joint angle decreases
Extension-joint angle increases
Adduction- body parts move towards midline
Abduction-body parts move away from midline
Rotation- body part moves around its own axis
Circumduction- body part moves so that cone shape is outlined
Inversion- sole of foot turns inward
Eversion- sole of foot turns outward
Structure of bone:
bone is alive, has nerves, blood supply, cells, connective tissue very organized in layers around blood vessels, cells make bone tissue, dissolve bone tissue, live inside bone tissue
Fetal bone formation: cartilage model forms first, then bony tissue fills around blood vessels, final bone has three parts central shaft diapysis, and 2 ends epiphysis, new bone tissue forms with in cartilage
Medullary Cavity: inside diaphysis is hollow tube, filled with bone marrow where blood cells form.
Calcium Regulation and Bone:
Bone serves as calcium storage, calcium is needed for many aspects of cell metabolism, but especially in muscle cells. Calcium regulation is negative feedback mechanism, release of calcium by degrading bone can be contrery to support role of bone, osteoporosis is a result of calcium need
No comments:
Post a Comment